Detalhe da pesquisa
1.
Tackling COVID-19 with neutralizing monoclonal antibodies.
Cell
; 184(12): 3086-3108, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34087172
2.
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.
Cell
; 184(9): 2332-2347.e16, 2021 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761326
3.
Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell
; 183(4): 1024-1042.e21, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32991844
4.
Tackling COVID-19 with neutralizing monoclonal antibodies.
Cell
; 184(17): 4593-4595, 2021 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34416148
5.
A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature
; 618(7965): 590-597, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37258672
6.
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.
Nature
; 593(7857): 136-141, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33706364
7.
Broad sarbecovirus neutralization by a human monoclonal antibody.
Nature
; 597(7874): 103-108, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34280951
8.
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature
; 583(7815): 290-295, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32422645
9.
Author Correction: A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature
; 619(7970): E50, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37407829
10.
Potent broadly neutralizing antibody VIR-3434 controls hepatitis B and D virus infection and reduces HBsAg in humanized mice.
J Hepatol
; 79(5): 1129-1138, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37459920
11.
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.
Nature
; 608(7922): E24, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35864232
12.
High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Nature
; 513(7516): 124-7, 2014 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043059
13.
Discovery of benzimidazole derivatives as orally active renin inhibitors: Optimization of 3,5-disubstituted piperidine to improve pharmacokinetic profile.
Bioorg Med Chem
; 26(12): 3261-3286, 2018 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29754833
14.
Structure-based design, synthesis, and biological evaluation of imidazo[1,2-b]pyridazine-based p38 MAP kinase inhibitors.
Bioorg Med Chem
; 26(3): 647-660, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29291937
15.
How a Potent Anti-neuraminidase Monoclonal Antibody Navigates Recent Immune-evasive Influenza Strains: A Structural Study by Single-particle CryoEM.
Microsc Microanal
; 29(29 Suppl 1): 927, 2023 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37613467
16.
Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design.
Bioorg Med Chem
; 25(17): 4876-4886, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760529
17.
Novel approach of fragment-based lead discovery applied to renin inhibitors.
Bioorg Med Chem
; 24(22): 6066-6074, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27720325
18.
Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors.
Bioorg Med Chem
; 24(22): 5771-5780, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27687967
19.
Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCθ inhibitors.
Bioorg Med Chem
; 24(11): 2466-75, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27117263
20.
Design, synthesis, and biological activities of novel hexahydropyrazino[1,2-a]indole derivatives as potent inhibitors of apoptosis (IAP) proteins antagonists with improved membrane permeability across MDR1 expressing cells.
Bioorg Med Chem
; 21(24): 7938-54, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24169315